| |
| Thesis Name： |
Analysis of signal transduction networking using activation ratios |
| Usage： |
Chemical Engineering |
| Keyword： |
Chemical Engineering |
| Remarks： |
The molecular processes by which information is incorporated and distributed within a cell are termed signal transduction. These pathways allow cells to interact with each other and with their environments and are critical to the proper cellular function in a variety of contexts. Previously developed methods for analyzing signaling networks have been largely ignored, most likely due to their mathematical complexity and difficulty in application. A novel analysis framework was developed to assist in the examination of signaling networks, both to facilitate the reconstruction of previously undetermined pathways as well as to quantitatively characterize interactions between components. This approach, termed activation ratio analysis, involves the ratio between active and inactive forms of signaling intermediates at steady state. The activation ratio of an intermediate is shown to depend linearly upon the concentration of the activating enzyme. The slope of the line is defined as the activ... |
| Original file： |
No File
|
|
Promulgator Detail |
| Full name: |
lorry |
| Country: |
CN |
| City: |
dalian |
| Company Name: |
Teloon corporation |
| Homepage: |
http:// |
| E-mail: |
reply |
| Phone: |
0411-82811662 |
| Fax: |
86-411-82819667 |
| Company Address: |
remin road,dalian city,liaoning,china |
| Zip/Postal Code: |
116001 |
| Introduction: |
Founded in 1994, Teloon Chemicals Corporation is a professional chemical exporter and producer in China. TeloonChem is located in the beautiful coastal city Dalian, the trade, commercial and financial center of Northeast China. |
|
|
|
|
